科学

IEEE计算机学会南京分会学术报告系列

IEEE CS Nanjing Chapter 5月10日15:30~16:30在南京大学蒙民伟楼404举行学术报告会,信息如下。欢迎参加!

题目:Transcriptome analysis for identifying stress-inducible microRNAs

报告人:Weixiong Zhang

Department of Computer Science and Engineering

Department of Genetics

Washington University in St. Louis

http://www.cse.wustl.edu/~zhang

时间:5月10日15:30-16:30

地点:蒙民伟楼404室

摘要:MicroRNAs (miRNAs) are ~21nt non-coding RNAs that regulate gene expression at the post-transcriptional level. Plant miRNAs regulate many genes that are involved in development and stress response. Although a large number of miRNAs have been identified and studied, most of them remain to be functionally annotated. Experimental functional analysis is laborious and costly. It is, therefore, desirable to develop computational approaches to support and complement experimental approaches for miRNA functional analysis. In this talk I will describe a novel, machine learning/datamining approach for identifying microRNA genes in plants that are responsive to environmental stresses. Our overall approach consists of a new computational method for identifying cis-regulatory DNA sequences (motifs) from the promoters of mRNA genes, a method for predicting core promoters of miRNA genes, a new transcriptome-based gene expression modeling method, and experimental verification of mature miRNAs and miRNA precursors. We applied our approach to study cold-responsive microRNA genes in Arabidospsis thaliana. We predicted nineteen individual microRNAs in twelve miRNA families to be up-regulated in Arabidopsis seedlings under cold stress. Our experimental validation showed that among the twelve microRNA families, eight were differentially induced by cold and three were constantly expressed under cold stimulus. A promoter analysis also showed that these cold-inducible microRNA genes contain many known stress-related cis-regulatory elements in their promoters. I will also discuss putative transcriptional down-regulation pathways triggered by the induction of these microRNA genes. Particularly, our result indicated that auxin signaling pathways in Arabidopsis seedlings may be mediated by many microRNAs.

简介:Weixiong Zhang is a professor of Computer Science and of Genetics at Washington University in St. Louis, Missouri, USA. He received his B.S. and M.S. in computer engineering from Tsinghua University, Beijing, China, and his M.S. and Ph.D. in computer science from University of California at Los Angeles (UCLA). Professor Zhang’s research interests include computational systems biology and genomics, artificial intelligence, data mining, and combinatorial optimization. He has published more than 100 papers in these areas and is the author of a research monograph, State-Space Search: Algorithms, Complexity, Extensions and Applications, published by Springer in 1999. He is currently associate editors of PLoS Computational Biology, J. Alzheimer’s Disease, Artificial Intelligence, and AI Communications – The European Journal on Artificial Intelligence.

IEEE计算机学会南京分会学术报告系列

各位同仁:

IEEE CS Nanjing Chapter 5月4日16:00~17:00在南京大学蒙民伟楼404举行学术报告会,信息如下。欢迎参加!

Bayesian Ying-Yang System, Best Harmony Learning, and Five Action Circling

LEI XU

Proposed in 1995 and systematically developed over fifteen years, Bayesian Ying-Yang (BYY)  learning is a statistical approach for an intelligent system via two complementary Bayesian representations of a joint distribution on the external observation X and its inner representation R, called BYY system. A Ying-Yang best harmony principle is proposed for learning all the unknowns in the system, in help of an implementation featured by a five action circling.  BYY learning provides not only a general framework that accommodates typical learning approaches from a unified perspective but also a new road that leads to improved model selection criteria, automatic model selection during learning, and coordinated implementation of Ying based model selection and Yang based learning regularization. This talk introduces BYY learning principles, implementing techniques, and typical learning algorithms, in a comparison with other algorithms, particularly with the EM algorithm as a benchmark. These algorithms are summarized in a unified Ying-Yang alternation procedure with major parts in a same expression while differences simply characterized by few options.

Lei Xu, chair professor of Chinese Univ Hong Kong, Chang Jiang Chair Professor of Peking Univ, IEEE Fellow (2001-) and Fellow of International Association for Pattern Recognition (2002-), and Academician of European Academy of Sciences (2002-).  He completed his Ph.D thesis at Tsinghua Univ by the end of 1986, then joined Dept. Math, Peking Univ in 1987 first as a postdoc and then exceptionally promoted to associate professor in 1988 and to a full professor in 1992. During 1989-93 he worked at several universities in Finland, Canada and USA, including Harvard and MIT. He joined CUHK in 1993 as senior lecturer, as  professor in 1996 and chair professor in 2002. He has published a number of well-cited papers on neural networks, statistical learning, and pattern recognition, e.g., his papers got over 3200 citations according to SCI and over 5500 citations according to Google Scholar (GS), with the first 10 papers scored over 2000 (SCI) and 3600 (GS). One single paper has scored 750 (SCI) and 1211 (GS). He served as associate editor for several journals, past governor of international neural network society (INNS), a past president of APNNA, and a member of Fellow committee of IEEE CI Society. Also, he has received several national and international academic awards  (e.g., 1993 National Nature Science Award, 1995 INNS Leadership Award and 2006 APNNA Outstanding Achievement Award).

电气电子工程师协会(IEEE)中文网站http://cn.ieee.org今天正式发布!

据本人刚刚收到的消息 :)

电气电子工程师协会(IEEE)中文网站http://cn.ieee.org今天正式发布!

1984年IEEE在中国成立了首个分会-北京分会-并拥有100名会员。今天,IEEE在中国已经有超过5000名会员,7个分会,3个支分会,1个联合会和1个代表处,在中国的影响力不断扩大,并成为中国工程师和全球科技团体沟通和交流的纽带和桥梁。

IEEE中文网站的成立标志着IEEE为中国会员的服务提升至一个新的台阶。在这里,我们将为您提供IEEE的最新咨询,会议信息,中国境内活动,会员专享服务等等。我们会继续努力,也坚信我们的会员,为了人类美好明天而不断创新。

感谢加入我们一起庆祝IEEE中文网站的成立!欲知更多网站内容,敬请访问http://cn.ieee.org

此致

IEEE中国代表处

2010年3月22日

Dear IEEE Members:

IEEE Chinese Website http://cn.ieee.org Announcement today!

IEEE formed its first Chinese Section-Beijing Section-in 1984 with barely 100 members. Today, IEEE has more than 5,000 members, seven sections, three sub-sections, one council and one representative office. IEEE has expanded its efforts to establish links between China’s engineers and the global technical community.

The Establishment of IEEE Chinese website indicates IEEE membership services for the Chinese to upgrade to a new level. Here we are providing IEEE news, conference information, activities in China and China’s exclusive membership services. As we move forward, we are confident that our members will continue to innovate in the service of mankind.

Thank you for joining with us to celebrate Chinese website announcement! For more information, please visit http://cn.ieee.org .

Sincerely,

IEEE China office

March 22, 2010

关于IEEE802族协议文本的下载.

今天拿到我的博客访问记录里,有一位朋友在百度里搜索IEEE802.15.4的协议文本下载,并且来到了我的博客。我饶有兴致的看了看怎么回事。原来百度里一堆不想关的页面列在首页,我的博客也忝列其中。

看来还是有人不知道在哪里下载IEEE的802族协议文本。IEEE802协议族,由于广泛流行,长了IEEE标准化协会的很大面子。所以IEEE802族协议,是可以在其官方网站上免费下载的。网址是

http://standards.ieee.org/getieee802/

或许朋友们可以在若干个协议文本里搜索到我的名字哦 Wenhao Zhu,呵呵。比如在 802.15.4c协议里。

由于相关许可协议限制,我不能把该协议文本贴在我的博客上,我也建议您不要做。以下是许可协议摘录

COPYRIGHT

This IEEE Standards Publication ("Document") is approved by the IEEE Standards Association ("IEEE-SA") Standards Board and is published in accordance with established IEEE-SA Standards Board bylaws and operations procedures.

The Institute of Electrical and Electronics Engineers, Inc., ("IEEE") owns the copyright to this Document in all forms of media. Copyright in the text retrieved, displayed or output from this Document is owned by IEEE and is protected by the copyright laws of the United States and by international treaties. The IEEE reserves all its rights not expressly granted herein.

The IEEE is providing the Document to you at no charge. However, the Document is not to be considered "Public Domain", as the IEEE is, and at all times shall remain, the sole copyright holder in the Document.

TERMS OF USE

You may retrieve, download and print one (1) copy of this Document for your personal use. You may retain one (1) additional copy of this Document as your personal archive copy.

Except as allowed by the copyright laws of the United States of America or applicable international treaties, or as explicitly allowed in these Terms of Use, you may not further copy, prepare, and/or distribute copies of this Document, nor significant portions of the document, in any form, without prior written permission from the IEEE.

Requests for permission to reprint this Document, in whole or in part, or requests for a license to reproduce and/or distribute this Document, in any form, must be submitted via email to Standards Licensing and Contracts, or in writing at:

IEEE Standards Association
445 Hoes Lane
Piscataway, NJ 08855-1331, USA.

不仅IEEE的这类标准可以下载,ITU的几乎所有标准都可以很容易的从官网上下载到相关文件。

最后建议一下,搜索这些东西,尽量用英语关键词,尽量用Google.com

WindowsLiveWriter27686f155f79_BF482009072901_8.png

认识这些塑料瓶上的标志么?

本文在署名-非商业性使用-相同方式共享 3.0版权协议下发布, 图片由 WikiMedia 在署名-相同方式共享 3.0版权协议下提供, 转载请注明出自aifreedom.com

2009072901

你有没有注意过平时使用的饮料瓶上都有一个这样的标志, 它表示什么?

所有人都知道那个"箭头围成的三角形"表示它可以被回收再利用. 但圈里那个数字和下面的字母是什么呢?

这个顺时针旋转的箭头形成的三角形和它里面的数字一起, 叫做塑胶分类标志 (Resin identification code).

很多人误以为有这个标志就意味着这个塑料制品是可以回收的, 而这个数字表示这个材料被回收的难度或者频率. 其实这个数字只是一个编号, 是美国塑胶工业协会制订的分类编码方式, 不同的编号表示不同种类的塑料材料. 而且虽然绝大多数塑料都可以回收, 但需要根据它们是不同的聚合物种类来分类. 而且由于挑选, 分类, 清洁和再加工等工序的成本, 目前经济上只能应付回收聚对苯二甲酸乙二酯(PET)与高密度聚乙烯(HDPE). 看这个 "PET" 是不是很眼熟? 上面那个标志就是 "PET" 塑料的标志. 我们平时用的大多数矿泉水, 碳酸饮料的瓶子就是用它做的.

不同种类的塑料制品的物理化学性质是有区别的. 例如除了PP塑料之外的大部分塑料都不耐热, 而不耐热的塑料制品遇热就容易释放出有毒的, 致癌的物质.

下面的塑料性质介绍来自网络. 部分内容我在 Wikipedia 上找到了相关资料, 但我没有查证以下所有描述, 不保证它们完全准确. 如果有任何错误请留言指出.

2009072901

1. PET 聚对苯二甲酸乙二醇脂

常见矿泉水瓶, 碳酸饮料瓶等. 耐热至70℃, 易变形, 有对人体有害的物质融出. PET塑料品用了10个月后, 可能释放出致癌物DEHP. 不能放在汽车内晒太阳; 不要装酒, 油等物质.

2009072902

2. HDPE 高密度聚乙烯

常见白色药瓶, 清洁用品, 沐浴产品的塑料瓶. 不要再用来做为水杯或者用来做储物容器装其他物品. 不要循环使用.

2009072903

3. PVC 聚氯乙烯

常见雨衣, 建材, 塑料膜, 塑料盒等. 可塑性优良, 价钱便宜, 故使用很普遍, 只能耐热81℃. 高温时容易释放有毒物质, 很少被用于食品包装. 不要循环使用. 若装饮品不要购买.

2009072904

4. PE 聚乙烯

常见保鲜膜, 塑料膜等都是用PE材料制作. 根据高中化学知识, PE本身是没有毒的. 但塑料制品在制作时会添加小分子的助剂, 它们通常是有毒的. 在高温下有毒的助剂容易迁移到塑料制品的表面. 如果用它来装高温的食物, 有毒物质随食物进入人体后, 可能引起乳腺癌, 新生儿先天缺陷等疾病. 所以别把保鲜膜放进微波炉.

2009072905

5. PP 聚丙烯

常见豆浆瓶, 优酪乳瓶, 果汁饮料瓶, 微波炉餐盒. 熔点高达167℃, 是唯一可以放进微波炉的塑料盒, 可在小心清洁后重复使用. 需要注意, 有些微波炉餐盒, 盒体以5号PP塑料制造, 但盒盖却以1号PE塑料制造. 由于PE不能抵受高温, 故不能与盒体一并放进微波炉.

2009072906

6. PS 聚苯乙烯

常见碗装泡面盒, 快餐盒. 不能放进微波炉中, 以免因温度过高而释出化学物. 装酸(如柳橙汁), 碱性物质后, 会分解出致癌物质. 别用微波炉煮碗装方便面, 或者干脆和我一样戒掉方便面.

2009072907

7. OTHER 其它类 (包括ABS树脂聚甲基丙烯酸甲酯聚碳酸酯聚乳酸尼龙玻璃纤维强化塑胶)

常见水壶, 太空杯, 奶瓶, CD 光盘, 桶装水瓶都是用这一类里的 PC 塑料制作, 容易释放出双酚A. 关于双酚A对人类的影响, 说法不一. 但加拿大政府已宣布双酚A是一种危险的化学品, 并正式将双酚A列入有毒化学品名单, 禁止在制造婴儿奶瓶的过程中添加双酚A.[1] 使用时不要加热, 不要在阳光下直晒.